What is PRF?
Platelet Rich Fibrin (PRF) facial rejuvenation.
PRF (Platelet-Rich Fibrin) from CosmoFrance is a natural, regenerative treatment derived from the patient’s own blood. It is used in aesthetics and medical applications to promote collagen production, enhance skin rejuvenation, and accelerate healing. Unlike Platelet-Rich Plasma (PRP), PRF contains a higher concentration of growth factors and fibrin, allowing for slower release and longer-lasting benefits.
How PRF Works
- Blood Draw: A small sample of blood is taken from the patient.
- Centrifugation: The blood is spun in a special low-speed centrifuge, which separates PRF without anticoagulants (unlike PRP).
- Injection or Microneedling: The PRF is applied to targeted areas via injection or combined with treatments like microneedling.
What are the Benefits of PRF
- 100% Natural & Autologous – No synthetic additives, reducing risk of allergic reactions.
- Gradual & Long-Lasting Results – Growth factors are released over time, stimulating collagen and elastin production.
- Skin Rejuvenation – Improves skin tone, texture, and elasticity while reducing fine lines and wrinkles.
- Faster Healing – Speeds up post-procedure recovery and wound healing.
What does PRF help with?
- Under-eye hollows (reducing dark circles and fine lines)
- Face, neck, and décolletage for anti-aging benefits
- Hands and scars for skin texture improvement
How long does it take?
You may choose to do it in one month or every 3-6 months based on your budget and time available for the procedure and downtime.
The downtime is usually one day but the swelling in the injected areas might last 3-5 days.
Who should avoid this?
- You should not have PRP/PRF treatment done if you have any of the following conditions:
- Skin conditions and diseases including: Facial cancer, existing or uncured.
- This includes SCC, BCC and melanoma, systemic cancer, chemotherapy, steroid therapy, dermatological diseases affecting the face (i.e. Porphyria), Blood disorders and platelet abnormalities, Anticoagulation therapy (i.e.: Warfarin).
- You also need to notify your doctor if you suffer from: Platelet dysfunction syndrome, critical thrombocytopenia, hypofibrinogenaemia, haemodynamic instability, sepsis, chronic liver disease, Hepatitis or any acute or chronic infections.
- Taking any of these medications can cause thinning of your blood if taken during 2 weeks prior to the procedure: Aspirin, Anti-inflammatory ( NSAID) such as Nurofen, Votaren, Diclofenac, Naproxen, Ibuprofen, Aleve, etc.; St Johns Wort, Garlic, Vitamin E, Inositol, Garlic, Omega 3, Boswellia, Bromelain, Gingko, Padora, Policosanol, Mesoglycan, Ginger, Green tea, Co-Q10, Epo ( Evening primrose oil).
Pictured here is the patient’s appearance less than 24 hours after Injection/Microneedling.⬇️
Dr. Izadi’s actual patient, subject to copyrights.
Dr. Izadi’s actual patient, subject to copyrights.
Dr. Izadi’s actual patient, subject to copyrights.
Dr. Izadi’s actual patient, subject to copyrights.
Scar removal with PRF
Dr. Izadi’s actual patient, subject to copyrights.
Why Choose Pristine Wellness?
At Pristine Wellness Center, Dr. Izadi, our esteemed medical director, personally performs every PRF/PRP procedure. As one of the most experienced medical professionals working with these procedures, she has achieved a remarkably high success rate, as reflected in her patients’ glowing testimonials.
Dr. Izadi is a quadruple board-certified physician with extensive expertise in functional and integrative medicine. She continuously enhances her knowledge by traveling the world, learning from leading doctors and scientists, and bringing the most advanced techniques back to her patients.
At Pristine Wellness Center, we pride ourselves on offering highly personalized care in a concierge-style setting—all at an affordable price, making top-tier treatments accessible to the average American.
Experience the difference in care and expertise at Pristine Wellness Center.
Rejuvenate and restore your youthful glow.
Our PRF Facial procedure is very safe and low-impact, bringing you a simply beautiful results.
PRF Vs. PRP - What's the Difference?
| Feature | PRF (Platelet-Rich Fibrin) | PRP (Platelet-Rich Plasma) |
|---|---|---|
| Processing Speed | Low-speed centrifugation | Higher-speed centrifugation |
| Additives | No anticoagulants | Uses anticoagulants |
| Growth Factor Release | Slow & sustained (up to 7 days) | Immediate release, short-lived |
| Fibrin Matrix | Forms a Fibrin network for prolonged effects | No Fibrin, effects fade faster |
Preparation & Care for PRF Treatment
Before Treatment
Stop taking any of these medications, that can cause thinning of your blood, 2 weeks prior to the procedure:
- Aspirin
- Anti-inflammatory (NSAIDs) such as Nurofen, Votaren, Diclofenac, Naproxen, Ibuprofen, Aleve, etc.
- St Johns Wort, Garlic, Vitamin E, Inositol, Garlic, Omega 3, Boswellia, Bromelain, Gingko, Padora, Policosanol, Mesoglycan, Ginger, Green tea, Co-Q10, Epo ( Evening primrose oil).
After Treatment
You will likely experience mild to moderate swelling of the treated area, this will last for about 12-24 hours; ice or cold compresses can be applied to reduce swelling if required.
You may notice a tingling sensation while the cells are healing.
Healing and Results
Due to the natural variation in quality of Platelet rich plasma, results will vary between individuals. Each person has different amount and type of growth factors and cytokines…
Although patients may see a change after the first treatment; they may require a series of multiple sessions to obtain the desired outcome.
Disclaimer
PRP/PRF is not FDA approved for the purpose of hair restoration or facial rejuvenation and its use for the purpose of restoration and rejuvenation is off-label.